Tissue distribution of cloxacillin after intramammary administration in the isolated perfused bovine udder
نویسندگان
چکیده
منابع مشابه
Tissue distribution of cloxacillin after intramammary administration in the isolated perfused bovine udder
BACKGROUND Various intramammary suspensions containing cloxacillin benzathine are registered for use in cattle as antibiotics for intramammary use at drying off. To ensure antibacterial efficacy, the glandular tissue concentration of an antimicrobial agent must be sufficient. Since the possibilities to measure concentrations in the different areas of the glandular tissue in vivo are very limite...
متن کاملSynthesis of milk fat from acetic acid (CH3 14COOH) by the perfused isolated bovine udder.
The technique of perfusion of the isolated udder is likely to give valuable information on the mechanisms of milk formation, provided it can be shown that most of the milk collected is actually a product of the secretory activity of the gland during the experiment. This point is not easy to demonstrate by ordinary chemical methods, because present-day techniques only permit of a rather limited ...
متن کاملp-Hydroxybutyrate and Acetate Metabolism of the Perfused Bovine Udder*
It was established by Shaw and Knodt (I) that the normal lactating udder (in situ) of the cow utilizes almost 2 mg. of phydroxybutyric acid per 100 ml. of blood traversing the udder; it was calculated that this was sufficient to account for the short chain fatty acids of milk fat or for about 40 per cent of the oxygen consumption of the secreting gland if it were oxidized for energy purposes. L...
متن کاملbeta-Hydroxybutyrate and acetate metabolism of the perfused bovine udder.
It was established by Shaw and Knodt (I) that the normal lactating udder (in situ) of the cow utilizes almost 2 mg. of phydroxybutyric acid per 100 ml. of blood traversing the udder; it was calculated that this was sufficient to account for the short chain fatty acids of milk fat or for about 40 per cent of the oxygen consumption of the secreting gland if it were oxidized for energy purposes. L...
متن کاملThe Isolated Perfused Bovine Liver
1. A procedure is described for surgically isolating and artificially perfusing the liver of the young bovine. Heparinized autogenous blood from the hepatectomized animal diluted with Krebs-Ringer-bicarbonate solution is employed as the perfusate. 2. This preparation has been satisfactorily reproducible in this laboratory in more than 90 separate sequential perfusions. Absence of a sensitive he...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Veterinary Research
سال: 2010
ISSN: 1746-6148
DOI: 10.1186/1746-6148-6-46